Skin rejuvenation therapies have evolved far beyond basic skincare
From cutting-edge exosome technology (ASCE+ SRLV) to well-established treatments like PRP, Skin Boosters, and Polynucleotides (PNs), each method offers unique advantages depending on your skin’s needs. This comparison helps you choose what suits your skin best—whether you seek hydration, regeneration, repair, or natural glow
| 🔍 Feature | 🧬 ASCE+ SRLV (Exosomes) | 🩸 PRP | 💧 Skin Boosters | 🧪 Polynucleotides (PNs) |
|---|---|---|---|---|
| 🔬 Source | Lab-derived stem cell exosomes | Your own blood (centrifuged) | Hyaluronic acid (synthetic/biotech) | Salmon DNA-derived molecules |
| ✨ Main Function | Regeneration, inflammation reduction, collagen boost | Tissue healing, collagen stimulation | Deep hydration and plumping | DNA repair and skin renewal |
| 📌 Best For | Dullness, pigmentation, aging, post-laser recovery | Fine lines, scars, under-eye texture | Dry, tired-looking skin, early aging | Sensitive, rosacea-prone, healing support |
| ✔️ Ideal For | Who wants advanced results without using their own blood (unlike PRP), and it’s particularly effective for sensitive, aged, or post-procedure skin | Who wants natural rejuvenation without synthetic ingredients | Who wants more on hydration and volume rather than cellular repair | Who uniquely suited for sensitive, inflamed, or post-acne-prone skin, making them a favorite for rosacea and barrier-impaired skin |
| ✅ Benefits | • Stimulates collagen and elastin • Reduces inflammation • Accelerates post-laser and microneedling recovery • Evens skin tone and texture • No blood required • Fast healing, minimal downtimen |
• Natural autologous treatment using your own blood • Promotes tissue healing and collagen production • Improves under-eye hollows, scars, and texture • Safe for most skin types |
• Deep, long-lasting hydration • Improves elasticity, plumpness, and glow • Minimally invasive with quick recovery • Good option for all skin types • Can be used preventatively |
• Repairs DNA damage at cellular level • Enhances barrier function • Calms inflammation and supports healing • Excellent for rosacea, redness, and post-inflammatory hyperpigmentation |
| ⚠️ Risks | • Temporary redness or sensitivity • Mild swelling at application site • Rare allergic reaction to peptides or excipients |
• Mild bruising, swelling, or pain • Risk of infection if not sterile • Results vary based on patient’s platelet quality |
• Small bumps at injection sites • Bruising or redness • Rare chance of lumpiness or uneven texture if improperly injected |
• Mild redness or sensitivity post-injection
• Temporary swelling or itching • Slight discomfort during injection process |
| 🎯 Treatment Areas | Face, neck, hands, décolletage | Face, scalp, under-eyes | Face, neck, hands | Face, neck, under-eyes |
| 🛠 Application Method | Microneedling, RF, post-laser | Microneedling or injections | Microinjections (mesotherapy) | Microneedling or microinjections |
| 🗓 Sessions Needed | 3–6 every 2–4 weeks | 3–4 every 4 weeks | 3–4 every 2–3 weeks | 3–5 every 2–4 weeks |
| ⌛ Downtime | Minimal | Minimal to mild | Minimal | Minimal to none |
| 🌟 Visible Results | Glowing, firm, smooth skin in 2–4 weeks | Texture, brightness, repair in 2–3 weeks | Hydrated, plump skin in 1–2 weeks | Improved clarity, calmness in 2–3 weeks |
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✓ Cellular Regeneration: Delivers lab-derived exosomes that signal cells to regenerate, boosting collagen, elastin, and overall skin vitality.
✓ Anti-inflammatory Action: Ideal for post-procedure skin and redness-prone clients due to strong inflammation-reducing properties
✓ Skin Brightening: Helps fade pigmentation and evens out tone due to its ability to regulate melanogenesis
✓ Non-blood-based: Perfect for patients unwilling or unable to undergo blood draw, unlike PRP
✓ Fast Recovery: Accelerates healing post-laser, microneedling, or RF treatments
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✓ Natural and Autologous: Uses the patient’s own blood components, making it safe, biocompatible, and less likely to cause adverse reactions
✓ Tissue Repair and Healing: Rich in growth factors that stimulate fibroblasts, enhance vascular supply, and accelerate tissue repair.
✓ Improves Texture and Scars: Particularly effective for acne scars, fine lines, and crepey under-eye skin
✓ Versatile: Can be used on the scalp for hair growth and face for rejuvenation
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✓ Intense Hydration: Restores moisture from within, giving skin a supple, dewy, and fresh appearance
✓ Elasticity and Firmness: Hyaluronic acid helps retain water, leading to firmer, plumper skin
✓ Quick Results: Visible improvement in hydration, glow, and fine lines in as little as 1–2 weeks
✓ Preventative Care: Suitable for younger clients or as a maintenance treatment to slow aging
✓ Versatile: Can be used on the face, neck, hands, and even under the eyes
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✓ DNA Repair and Regeneration: Stimulates cellular repair, particularly effective for damaged or inflamed skin
✓ Anti-Inflammatory & Healing: Calms reactive, acne-prone, or rosacea skin; often used post-procedure
✓ Improves Barrier Function: Increases hydration and strengthens the skin barrier against environmental stressors
✓ Safe for Sensitive Skin: Ideal for clients who cannot tolerate aggressive treatments or have compromised skin
✓ Skin Clarity & Tone: Over time, improves tone, clarity, and reduces post-inflammatory hyperpigmentation
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⚠︎ Mild Redness or Irritation: Temporary erythema or tingling may occur post-application, especially when microneedled.
⚠︎ Allergic Sensitivity: Though rare, some clients may react to peptides or carrier ingredients.
⚠︎ Product Source Sensitivity: As lab-derived biologics, reactions can vary slightly across individuals
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⚠︎ Bruising and Swelling: Injections may cause temporary puffiness or bruising, especially around delicate areas.
⚠︎ Infection Risk: As with any injection, sterility is essential to avoid complications.
⚠︎ Variable Efficacy: Results depend on the patient’s platelet quality, hydration, and general health.
⚠︎ Not Ideal for All: Patients with anemia, clotting disorders, or blood diseases may be ineligible
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⚠︎ Injection Site Reactions: Redness, tenderness, or small bumps can appear and usually resolve in a few days.
⚠︎ Lumpiness: In rare cases, over-injection or poor placement can cause uneven texture or nodules.
⚠︎ Short-Term Results: Hydration effects may need regular maintenance every few months.
⚠︎ Allergic Reactions: Rare but possible in clients with sensitivity to cross-linked HA or preservatives
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⚠︎ Mild Swelling or Redness: Temporary and resolves quickly
⚠︎ Discomfort During Injection: Some patients report stinging or warmth during treatment
⚠︎ Slow Results: Compared to HA or exosomes, benefits may take a few weeks to manifest visibly
⚠︎ Multiple Sessions Needed: Best results occur after a full treatment course
Choosing the right treatment depends on your skin concerns, sensitivity level, and aesthetic goals:
Want cutting-edge results with rapid recovery? ASCE+ SRLV is your go-to
Prefer a natural, regenerative approach? PRP offers safe, proven results using your own biology
Need hydration and a glow-up before an event? Choose Skin Boosters
Struggle with inflammation, rosacea, or a weakened skin barrier? Polynucleotides are a gentle yet powerful solution
💡 With professional assessment, the right treatment—or a combination—can be tailored to help you achieve radiant, youthful skin with lasting results. Let us help you make the best choice for your skin’s unique needs.